DSIP

Name: BPC-157
Brand: Limitless Peptides
SKU: BPC-157-10-601
Price: 99.00 USD
Availability: InStock

Purity: 99.729%

Batch #: DSIP-5-601

Verified Potency: 5.97mg

$55.00

DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring neuropeptide investigated for its influence on sleep architecture, stress adaptation, and neuroendocrine balance.

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Disclaimer

For Research Use Only. Not for human consumption or therapeutic treatment.

About DSIP

Delta Sleep-Inducing Peptide (DSIP) is a nine-amino-acid neuropeptide that has captivated researchers for its multifaceted effects on sleep quality, stress resilience, and pain modulation pathways. Scientists explore DSIP's influence on natural sleep-wake cycles, hypothalamic-pituitary-adrenal axis regulation, and overall neurochemical harmony. Its mechanisms continue to intrigue the research community, with ongoing studies investigating how it interacts with multiple neurotransmitter systems and endocrine pathways to promote restorative physiological states. DSIP has become a valuable tool in sleep science and studies examining how neuropeptides orchestrate the body's natural recovery and adaptation processes.

Product Specifications

DSIP Lyophilized Powder in 3ml vial

Application

Sleep regulation, stress response, and neuropeptide research

Appearance

Solid, white powder in 3mL glass ampule

Chemical Formula

C35H48N10O15

CAS number

62568-57-4

Molecular Weight

~848.8 g/mol

FAQs

What is DSIP?

DSIP, or delta sleep-inducing peptide, is a nonapeptide with the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu. It was first isolated in 1977 from the cerebral venous blood of rabbits during electrically induced slow-wave sleep by Schoenenberger and Monnier. DSIP has a molecular weight of approximately 849 Da and crosses the blood-brain barrier. It is found in both the central nervous system and peripheral tissues, including the adrenal glands and gastrointestinal tract.

What is DSIP researched for?

DSIP is studied for its effects on sleep architecture, stress response modulation, and neuroendocrine regulation. Research reports that DSIP administration promotes delta-wave (slow-wave) sleep in animal models, reduces corticotropin-releasing factor levels, and modulates ACTH and cortisol secretion patterns. Additional research areas include its effects on pain perception thresholds, opiate withdrawal symptoms, and circadian rhythm regulation.

How does DSIP affect sleep patterns in research?

Studies in rabbit and rat models report that DSIP administration increases the proportion of time spent in slow-wave sleep without significantly altering total sleep duration. The peptide's effects on sleep architecture appear to involve modulation of serotonergic and GABAergic neurotransmission rather than sedation. Unlike benzodiazepines, DSIP does not suppress REM sleep or produce tolerance in animal models, which is a studied distinction in sleep pharmacology research.

Does DSIP affect the stress response axis?

Published research reports that DSIP modulates the hypothalamic-pituitary-adrenal axis. Administration in animal models reduces stress-induced elevations of ACTH and cortisol and attenuates corticotropin-releasing factor release from the hypothalamus. Studies also describe normalization of disrupted circadian cortisol rhythms in stressed animal models, suggesting DSIP interacts with both the stress response and circadian regulatory systems.

Can I buy DSIP for research?

Limitless Peptides sells DSIP as a lyophilized powder in a sealed 3mL glass ampule. The product is Janoshik verified for identity, potency, and purity. DSIP is sold for research use only and is not approved for human consumption. The product page includes the manufacturer's certificate of analysis and a link to the independent Janoshik verification report.

DSIP

About DSIP

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